Гигиена детей и подростков
Гигиена питания
Токсикология
PSYCHOPHYSICAL DEVELOPMENT AND STATE OF HEALTH OF THE SENIOR PRESCHOOL CHILDREN OF COMPENSATING ORTHOPEDIC GROUPS
Scientific research institute of hygiene and health protection of children and teenagers Russian Academy of Medical Science, Moscow
The evaluation of the health state, psychological status and physical preparedness in preschools aged of 5-7 years with orthopaedic disorders were carried. It have been established the fact that this group of children suffers from chronic diseases more than 2 times oftener than children at the same age who haven't these disorders. Besides that this group of children has normal physical development rarely and they have low level of physical preparedness more often (it is proved to be that than 50% of those children run slowly).
USE OF METHODOLOGY OF THE ESTIMATION OF RISK IN REGIONAL SYSTEMS OF MONITORING OF HEALTH OF THE CHILDREN'S POPULATION OF LARGE INDUSTRIAL CITY
State Medacal Academy, N.Novgorod, Russia
Thus, results of long-term complex monitoring of quality of an environment and health of the children's population in conditions of large industrial centre have shown, that the population of city during the long period of time is exposed to risk of development prenosological pathologies and ecologiassociated diseases.
ON THE HEALTH CONDITIONS OF CHILDREN IN BREST REGION
Brest regional center of hygiene, epidemiology and public health, Brest
The investigation performed shows the growth of both initial and general sickness rate of children in the region. The initial sickness rate has grown in 1,51 times and general sickness rate has grown in 1,44 times for a period of 13 years.
As a whole in the region in 6 year dynamics a growth in the number of children belonging by health to the 3rd and 4th groups is traced and a considerable decrease (1,5 times) of children belonging to the 1st group.
At the same time the analysis data allow to appreciate positively the existing system of rendering medical assistance to children. The lower growth rates of general sickness as compared with the growth of initial sickness prove the effectiveness of conducted prophylactic medical examination and preventive work.
In order to elaborate concrete programs and measures for improvement of health conditions of children in the region it is necessary to study the epidemiology of a number of uninfectious diseases more profoundly.
HEALTH CHARACTERISTIC OF SCHOOLCHILDREN IN LUNINETS DISTRICT, BREST REGION.
Brest regional center of hygiene, epidemiology and public health, Brest
For health evaluation of schoolchildren the results off all-round planned regular medical examination and additional fundamental medical and ecological survey of tenth form pupils have been used. According to the examination results the recommendations have been worked out to eliminate disorders in the children's health.
To decrease the content of xenobiotics in the organism, it is necessary to perform organism detoxication with the use of pectins and enterosorbents. The replacement of deficiency in the main idiopathic microelements can be provided primarily by appropriately made menu that includes a necessary set of food products. With the purpose of improvement of organism resistance it is necessary to make mass engagement in physical culture and sports avaiable, to introduce health -creating technologies directed rather towards creation and improvement of health than to its protection.
HYGIENIC EXEPERTISE OF TOYS: APPROACHES, PROBLEMS
Republican scientific - practical center of hygiene, Minsk
At the moment the perfection of the certification and hygienic registration system of all the children goods is an important and urgent direction in the field of children hygiene.
Since 1999 a constant monitoring of the quality and safety of the children toys has been carried out in the children and juvenile hygiene laboratory.
The creation of the data base, grounded on the results of hygienic expertise conduction and the following analysis of the received information creates the perspective for the further perfection of the standard and systematic documentation.
CONCERNING THE QUESTION OF THE HYGIENIC ESTIMATION OF THE QUALITY OF IN-SCHOOL ENVIRONMENT BY SECURITY INDEXES
Republican scientific - practical center of hygiene, Minsk
The employees of the leading departments of the Republican Scientific Practical Centre of Hygiene conduct the monitoring of the in-school environment by chemical and microbiological indexes. It includes the study of the level of chemical pollution of the air in school premises and by-highway places, adjoining the educational establishments; the study of the chemical contamination of the air in the main school premises; the study of the practical microbiological contamination of the air in school premises, and in the school environment objects.
According to the results of the work the project of the Instruction "The Complex Evaluation of the Quality of In-school Environment by Safety Indexes" has been prepared. It will define the algorithm of quality control of the in-school environment and the variants of its correction depending on the pointed violations of the hygienic standards. The points, stated in the Instruction could be further used for conducting the monitoring of the school environment condition in the practice of the running sanitary observation, and also for the measures development, aimed at the sanitation of the environment.
THE HYGIENIC CRITERIONS OF THE APPRECIATION OF THE QUALITY OF THE PRE-SCHOOL EDUCATION
Republican scientific - practical center of hygiene, Minsk
*Minsk city center of hygiene and epidemiology, Minsk
The intensification of the educational process in the pre-school institutions assists in developing of the memory, attention, perception and in the children's acquisition of definite habits, knowledge and skills, but the health protection demands the optimization of the educational programs, turning to raise the health reserves, to lowering the morbidity of the children of the pre-school age. The hygienic appreciation of the quality of the pre-school education must take into account indices of physical development, physical training and the state of children's health for the guarantee of the continuity of the pre-school and the primary school education.
THE HYGIENIC APPRECIATION OF THE CONDITION IN THE ORGANIZATION OF THE EDUCATIONAL ACTIVITIES OF THE PRE-SCHOOL CHILDREN
Republican scientific - practical center of hygiene, Minsk
The results of the researches show the necessity of the constant hygienic and psychological accompaniment of the educational activities of the children in the pre-school institutions, the search of new forms and methods of the teaching, included the dynamic component and turned to the forming of the inside positive children's motivation to the education. In the result of the carried out researches the hygienic recommendations were worked out in the organization of the adaptational educational surroundings in the pre-school institutions and arrangements turned to the preservation and the strengthening of the children's health.
ROLE OF HYGIENIC FACTORS IN THERAPY OF HYPERKINETIC FRUSTRATION AT CHILDREN
Republican scientific - practical center "Mother and child", Minsk
The experience in treatment of hyperkinetic disorders of attention and behavior in 85 children aged 5-6 allowed to work out a protocol of treatment such disordes in pre-school and young school children. This protocol includes the following directions:
The using of nootropic agents.
The administration of phytosedative and phytoadptogenic agents.
The administration of vitamins and microelements.
Psychological and pedagogical correction.
All the children who underwent 2 courses of medical therapy on the background continuous psychological-pedagogical correction revealed significant reduction of symptoms and improvement of social adaptation.
THE MAIN FORMS OF THE PREVENTION AND CORRECTION WORK IN A MODERN EDUCATIONAL ESTABLISHMENT
Republican scientific - practical center of hygiene, Minsk
The model of the prevention and correction work in a secondary educational establishment is offered. The duties of the administration, teachers, medical staff and psychologists are defined aiming at the minimization of the inner-school risk factors and the optimisation of the education taking into account the health preservation.
HYGIENIC ASPECTS OF THE ANALYSIS OF THE PATHOLOGY OF BODIES BREATH OF CHILDREN OF MINSK
Belarusian medical academy postgraduate educations, Minsk
The aim of the study is to determine the correlation between the contaminated atmospheric air and respiratory diseases in children living in Minsk. The atmospheric air in Minsk is characterized by the increased amount of formaldehyde, phenol, and ammonium. The main pathological respiratory conditions in children are amygdale and adenoid diseases, pneumonia and bronchial asthma.
INFLUENCE OF RECEPTION OF ВИТАМИНО-MINERAL COMPLEXES ON CURRENT OF PREGNANCY, SORTS AND CONDITION OF NEWBORN CHILDREN
Republican scientific - practical center "Mother and child", Minsk
*Research-and-production society with limited liability "Belinteranalit", Minsk
The objective of this study was to examine the association of prenatal multivitamin/mineral supplement use during pregnancy by urban women on concentration of microelements in blood in the third trimester, course of pregnancy and delivery, state of their newborns. The use of prenatal multivitamin/mineral supplement contributed to diminution of frequency of complications of pregnancy (anemia of pregnancy in the third trimester), positive influenced on development of fetus diminishing frequency of his growth retardation. The use of prenatal multivitamin/mineral supplement also resulted in decrease of the blood levels of toxic microelements (Cd, Sb, Sn) and increase concentration of essential elements (Fe). The authors proposed to use of prenatal multivitamin/mineral complexes not only on the basis of the daily requirements of all essential trace elements for a pregnant, but on the basis of a study of trace elements status of women until pregnancy. It is implied necessity of use of a method of multielements analysis.
ADAPTATION POTENTIAL AND MENTAL EFFICIENCY OF CONTEMPORARY SCHOOLCHILDREN
Belarusian state medical university, Minsk
Adaptation potential and mental efficiency of 9 year secondary school and gymnasium students were investigated. Contemporary schoolchildren demonstrate not quite high adaptation potential for unfavorable influence of the environment: only 34.6% of schoolchildren and 39.0% of gymnasium students show satisfactory adaptation.
The productivity of correction of schoolchildren is 2.5 times higher than that of gymnasium students. One out of five gymnasium students finishes an academic year being tired and exhausted and can be referred to the risk health group.
DYNAMICS OF FUNCTIONAL CONDITION OF THE CARDIOVASCULAR AND VEGETATIVE SYSTEM OF SECONDARY SCHOOL SENIOR STUDENTS
Belarusian state medical university, Minsk
Characteristics of the cardiovascular and vegetative system of 9 and 10 years senior students at gymnasium and a secondary school in Minsk were investigated. According to the endurance coefficient data, the cardiovascular system the endurance of gymnasium students is higher than that of secondary school children, both boys and girls. Training of the cardiovascular system is improving from 9 to 10 years of studies at gymnasium and school. The cardiovascular system of gym students is influenced by the parasympathyc nervous system, the same of secondary school children is affected by the sympathyc adrenalin system. The arterial pressure of 10 years gym students is worse than that of 10 year school children of secondary school. Children with high systolic arterial pressure more numerous at gymnasium than at secondary school. Girls arterial pressure is more favorable than that of boys both gymnasium and a secondary school.
SOCIAL ADAPTABILITY, VEGETATIVE STABILITY AND PSYCHO-EMOTIONAL CONDITION OF SECONDARY CHOOL SENIOR STUDENTS
Belarusian state medical university, Minsk
Social adaptability, vegetative stability and emotional condition of 9 year senior students in Minsk secondary school and gymnasium were investigated. A One out of five senior student demonstrates low social adaptability. 29.7% of gymnasium students and 43.3% of secondary school students are characterized by high vegetative lability. 60% to 75% of school students and 72% to 86% of gymnasium students are in good emotional condition.
ABOUT SANITARY-HYGIENIC CONDITIONS OF CHILDREN'S HEALTH IN SECONDARY SCHOOLS
Grodno state medical university, Grodno
Grodno regional centre of hygiene and epidemiology, Grodno
The essential factors that influence on children's health are conditions in which children stay at school. First of all, negative changes of their health are connected with violation of sanitary-hygienic conditions at school.
In such a way, the amount of chronic and typical for school pathologies increase, which
testify low level of adaptation to school loading.
THE CONTENTS OF MERCURY IN URINE OF WOMEN OF CHILDBEARING AGE
*Federal state scientific institution institute of toxicology federal medical - biological agency of Russian Federation, Saint-Petersburg
**Saint-Petersburg state pediatric medical academy, Saint-Petersburg, Russia
***Republican scientific - practical center of hygiene, Minsk
The authentic increase in the contents of mercury in urine of women in last trimester of pregnancy is established. This fact can become a basis of development noninvasiveness a quality monitoring of mercury in blood of pregnant women.
FEATURES OF EMOTIONAL SPHERE AT TEENAGERS WITH THE VARIOUS DEGREE OF QUALITY OF THE LIFE
Belarusian medical academy postgraduate educations, Minsk
The purpose of this work is to reveal features of emotional sphere in teenagers with various life quality degree. The estimation of teenagers' life quality was carried out using the questionnaire developed on the basis of definition of life quality given by the WHO. Conclusions: the average index of the studied teenagers' life quality is low. Rather low degree of life quality is accompanied by negative emotional states such as envy, despondency, etc., and relatively high level of life quality - positive emotional states such as pleasure, enthusiasm, etc.
THE FEATURES OF EMOTIONAL SPHERE AT TEENAGERS WITH THE VARIOUS DEGREE OF MORAL DEVELOPMENT
Belarusian medical academy postgraduate educations, Minsk
The purpose of the present research is to reveal features of personality's emotional sphere in teenagers with various degree of personal conceptions - values development on the basis of moral development parameter. Conceptions - values (spiritual - moral) development of the person was studied using the questionnaire for rating psychohygienic status developed by the authors. Conclusions: the per cent of teenagers with higher parameter of spiritual - moral development is higher among girls (57,5 % versus 46,7 % in boys). The correllation between the high level of spiritual - moral development and positive emotional states, such as pleasure, enthusiasm, interest, etc. has been shown.
INFLUENCE OF FACTORS OF ANTHROPOGENOUS INFLUENCE ON DESEASE RESPIRATORY INFECTIONS AT CHILDREN'S AGE
Republican scientific - practical center "Mother and child", Minsk
There were examined 100 children having repeated infections of respiratory tracts and living in area with a various degree of pollution .The I group- 60 children leaving on the area of Minsk with the high level of pollution, the control group - 40 children from the area with ecologically safe atmosphere. Children with frequent and long diseases of the top respiratory tracts are revealed dysbiotic infringements in a pharynx and an intestine, functional activity of factors of local immunity of a respiratory path that is shown in decrease in a level секреторного an antibody аnd in a saliva is lowered. As a result of the correlative analysis between the level of секреторного an antibody and the parameters describing a condition микробиоценоза of intestines return correlation interrelations (r = - 0,42 have been revealed; p <0,05). Children from the area with high level of pollution have lower sIgA level in saliva, than those from the areas with the most ecologically safe conditions.
DEPENDENCE OF PSYCHOLOGICAL-EMOTIONAL STATUS AT SECONDARY SCHOOL FROM FUNCTIONING ENVIRONMENTAL FACTORS
Republican scientific - practical center of hygiene, Minsk
The peculiar properties regularity of the joint effect combination of environmental factors (man-caused and interschool factors) on state of health of schoolchildren actually on psychological-emotional status at secondary school living at the different micro districts was revealed. Sanitary-epidemiological well-being level of general educational institution and separate risk factors of interschool environment has an influence to a considerable degree upon indices of schoolchildren neurotization.
RISKY SEXUAL BEHAVIOUR AND MORAL VALUES OF YOUNG PEOPLE FROM FULL AND INCOMPLETE FAMILIES
Byelorussian medical academy postgraduate education, Minsk
577 persons (students, parishioners of church, patients with venereal diseases) were examined by using questionnaire composed of 120 questions. It is not only the structure of family (complete, incomplete), but the level of satisfaction with relationship with parents influences the formation of liability to behavioral risks. The tendency of combination of smaller satisfaction with family microclimate and larger liability to behavioral risks and smaller significance of moral values was detected.INVESTIGATION OF THE INFLUENCE OF QUALITY OF VITEBSK' ENVIRONMENT TO CHILDREN'S HEALTH
RUP "BelNIC "Ecology", Minsk
Questions of creating of the territorial complex scheme of environmental protection of Vitebsk city is observed in the article. Results of the researching of influence of quality of environment of Vitebsk to children's health are given.
TO A QUESTION ON HYGIENIC EXAMINATION OF THE GOODS OF CHILDREN'S ASSORTMENT.
Republican scientific - practical center of hygiene, Minsk
At manufacturing the goods of children's assortment the wide spectrum of various polymeric and synthetic materials is used. Depending on structure of materials it is possible to assume an opportunity of allocation of various chemical substances. In laboratory of hygiene of children and teenagers the material by results of carrying out of hygienic examination of the goods of children's assortment collects and systematized with the purpose of development and perfection of methodological approaches to an estimation of parameters of hygienic safety.
SYSTEMATIC APPROACH TO THE HEALTH PRESERVATION IN THE SITUATION OF THE SCHOOL SYSTEM MODERNIZATION
State Establishment "Republican practical - scientific center of hygiene", Minsk
*Ministry of public health Republic of Belarus
**Health commission of Minsk state executive commission, Minsk
***Children's polyclinic 25, Minsk.
The instruction is created, where the algorithm of the joint actions of the educational process participants is represented aiming at health prevention: health diagnostics of the students, characteristics of the sanitary and epidemiological well-being of the establishment, definition of the risk factors, revelation of the cause-consequence connections, analytic-informative-statistic work with the later development of the strategy of every child's guidance.
HEALTH PRESERVATION AS THE BASIS OF THE EFFECTIVE CORE EDUCATION IMPLEMENTATION
Republican scientific - practical center of hygiene, Minsk
*Ministry of education Republic of Belarus
Ill-being health condition of students in connection with the transition of the high school to the core education puts forward the necessity of the hygienic study load norm system improvement, which in a lot of cases defines the preservation of the physiological and somatic health of the youth. The evaluation of the health risks connected with the differentiation of the education on the third level of the general school in the situation of the educational system modernization corresponds to the requirements of the social demand and is one of the main hygienic problems. The core education is to be viewed as a interdepartmental and interdisciplinary problem, in solving of which the state is highly interested.
DEFICIT OF THE ATTENTION SYNDROME WITH HYPERACTIVITY OF ELEMENTARY SCHOOL PUPILS AS A HYGIENE PROBLEM
Republican scientific - practical center of hygiene, Minsk
For the purpose of education and health prevention effectiveness of the elementary school pupils is the following relevant: epidemiological study of the occurrence of the deficit of the attention syndrome with hyperactivity; arrangement of the prevention activities complex aiming at the awareness and education of the future mothers in the field of the health life style; work security of the pregnant women; early detection of the children with the syndrome; Physiological en hygienic correction; creating the conditions for the child's education, adequate to his capabilities.
INFLUENCE METEOPATHIC REACTIONS ON CURRENT AND EPIDEMIOLOGY OBSTRUCTIVE DEFEATS OF RESPIRATORY WAYS AT CHILDREN IN MODERN ECOLOGICAL CONDITIONS OF LARGE INDUSTRIAL CENTRE
Republican scientific - practical center "Mother and child", Minsk
Monthly morbidity rate in acute laryngotracheitis (AL) and acute obstructive bronchitis (AOB) in all the children admitted in specialized departments from three large out-patient clinics of industrial zone of Minsk-city. AL and AOB rate for last years (2003 - 2004) was also compared with the number of meteorologic factors (air temperature, circardian changes in temperature, barometric pressure, relative air humidity and preliminary circadian wind direction). The analysis was made according to Hydrometeocentre data of the Republic of Belarus for the corresponding period.
The data represented by authors indicate the considerable statistically verified influence of the number of meteorological factors and their combinations on the pathogenesis and epidemiology of acute laryngotracheites and acute obstructive bronchites in children and, if more careful investigations would be made, may be used in practical health care for the prophylactics of these diseases.
THE ORGANIZATION OF EDUCATIONAL PROCESS IN SPECIAL EDUCATIONAL ESTABLISHMENTS AND ITS INFLUENCE ON PSYCHOLOGICAL AND FUNCTIONAL CONDITION OF DISABLED SCHOOLCHIDREN
Republican scientific - practical center of hygiene, Minsk
Peculiar properties of educational process organization in special educational establishments were studied. Dynamic of physiologic and functional conditions of disabled schoolchildren for the period of training in special schools was found out. Physiologic and functional conditions of disabled schoolchildren were getting worse to the end of studies (to the end of school day and week). It's proved that educational process organization didn't correspond to physiologic and functional possibilities of disabled schoolchildren. To purposeful process control of health forming in social environment as school hygienic requirements to the educational process need to be scientifically grounded and developed.
SANITARY-EPIDEMIC WELL-BEING OF SPECIAL EDUCATIONAL ESTABLISHMENTS
Republican scientific - practical center of hygiene, Minsk
Health state of children and teenagers depends on environmental factors. The level of sanitary-epidemic well-being of special educational establishments was estimated. In order to give more objective quantitative characteristic of the sanitary-and-hygienic parameters having is qualitative-quantitative categories we used an integrated approach to the estimation of sanitary-epidemic well-being. The integrated approach provides the unified technique of an estimation of conditions of training in educational establishment as one of the most significant and informative blocks of factors of an environment. The micro portrait of environment in concrete schools providing special education, reflecting its real characteristics is obviously possible. The most of sanitary-and-hygienic conditions provides minimal acceptable conditions of training. Negative dynamic of health status of disabled schoolchildren for the period of training in special schools was confirmed.
RESEARCHES MICROBIAL CONTAMINATION OF SCHOOL ENVIRONMENT
Republican scientific - practical center of hygiene, Minsk
The researches of objects of school environment were carried out. The results of the carried out researches have shown wide prevalence of microorganisms various taxonomy accessory, that testifies to sanitary - hygienic trouble and insufficiency of hygienic measures spent at school. The additional measures are necessary, among which, the important role will belong to preventive disinfection.
LACTULOSE AND METHODS FOR ITS DETERMINATIONS
Republican scientific - practical center of Hygiene, Minsk
It is shown that the most perspective method for the determination lactulose is high performance chromatography with using refractometric and electrochemical detectors.
DETERMINATION OF VITAMINS IN SPREDS
Republican scientific - practical center of hygiene, Minsk
The method, which allows to determine vitamin C content in spreds and others fat products has been developed.
VALIDATION OF THE METHOD FOR THE DETERMINATION OF SORBIC AND BENZOIC ACIDS TO NEW KIND OF FOODS, FOOD AND BIOLOGICAL ACTIVE ADDS
Republican scientific - practical center of hygiene, Minsk
*Belarusian medical academy postgraduate educations, Minsk
Validation of the method for the determination of sorbic and benzoic acids to new kind of foods, food and biological active adds by HPLC was carried out.
TO QUESTION ABOUT MONITORING ORGANOCHLORINE COMPOUNDS IN HUMAN BREAST MILK
Republican scientific - practical center of hygiene, Minsk
The influence of stable organochlorine contaminates on health. The necessity of carrying out monitoring of human breast milk pollutions by organochlorine pesticides and polychlorinated biphenyls is shown.
OPTIMISATION OF THE CODITION FOR FORMATION OF COMPLEX OF 4,5- PIASOSELENOL BY FLUORIMETRIC DETERMINATION OF SELENIUM
Republican scientific - practical center of hygiene, Minsk
Is shown that optimum conditions of reaction for condensation of selenium acids with 2,3-diaminonaphfthalene are: рН of solutions 1,5 - 2,0; temperature 40-50 0С, time of realization for reaction - 30 mines. The most acceptable solvent is the cyclohexane.
The realization of reaction for condensation under the above-stated conditions allows to increase accuracy of analysis selenium in the biological samples.
ABOUT INFLUENCE OF THE ADDITIVE FROM A LUPIN GRAIN ON A DEGREE OF HYDROLYSIS OF FIBERS OF THE COMBINED MEAT PRODUCTS PROTEOLYTIC ENZYMES < IN VITRO >
Mogilev state university of the foodstuffs, Mogilev
The results of researches of food and biological value of combined meat products with use of the protein additive from a lupin grain are resulted in the article.
The digestion rate of proteins under the effect of the proteolytic enzymes in vitro (pepsin, trypsin and combination of pepsin-trypsin) was used as one of biological value estimation criteria . As shown the developed combined meat products do not concede production with application of soy analogues.
RESEARCH OF INFLUENCE OF DURATION OF HYDROLYSIS - extracting protopectin IN THE CAPACITOR DEVICE WITH THE ACTIVE HYDRODYNAMICAL MODE ON THE OUTPUT AND QUALITY OF PECTIN
Mogilev state university of the foodstuffs, Mogilev
Influence of duration of process of hydrolysis - extracting protopectin from dried husks of apples in the capacitor device with an active hydrodynamical mode on an output and quality of received pectin is investigated. It is established, that duration of hydrolysis - extracting protopectin influences quality of received pectin and does not influence an output of pectin from structure of a vegetative fabric.
RESEARCH OF COMPLEX-FORMING ABILITY OF MASHED POTATOES FROM APPLE SQUEEZING
Belarusian trade and economic university of consumer's cooperative society, Gomel
The results of research of complex-forming ability of puree from apple squeezing canned by a sulphurous acid of various concentration are reflected. The certain law is established: complex-forming ability of pectin increases with reduction of percentage of an acid in a solution and with downturn of etherification degree.
INFLUENCE OF THE CONTENTS OF SUGAR AND INULIN ON PARAMETERS OF QUALITY OF SHORTCAKE
Mogilev state university of the foodstuffs, Mogilev
Ability to adsorption of a moisture cookies it is reduced with reduction of the contents of sugar. Dependence of density of cookies on the contents of sugar has parabolic character at the contents of sugar in an interval 60 - 40 % from weight of a flour decrease. In an interval 30 - 10 % the density of cookies raises. Inulin, entered into a compounding of the sand test, increases Ability to adsorption of a moisture the baked cookies increases it аbility to adsorption of a moisture and reduces density.
SUBSTANTIATION OF EXPEDIENCY OF APPLICATION OF A PREPARATION OF FOOD FIBRES FROM VEGETATIVE RAW MATERIAL BY MANUFACTURE OF CONFECTIONERY PRODUCTS SUCH AS "FRUIT CANDY FRUIT"
Mogilev state university of the foodstuffs, Mogilev
The expediency of use of complex preparations of the food fibres selected from vegetative raw material, is caused by presence in their structure of the pectinaceous substances having gelatinous properties. Introduction of preparations of food fibres in practice of confectionery manufacture considerably will allow to expand assortment of a domestic production with a gelatinous consistence and to raise efficiency of use of local vegetative raw material by manufacture of food stuffs. In the present work the opportunity of application of a preparation of food fibres from apple pomace "polycom" is proved by manufacture of confectionery products such as "fruit candy fruit".
FOOD ADDS FROM SECOND FRUIT-BERRY RAW MATERIAL AS ADDITIONAL SOURSE OF VITAMIN C
Republican scientific - practical center of hygiene, Minsk
It is shown, that the dried powders from second fruit-berry raw material contain considerable quantities of vitamin C and can be used as food adds for fortification of food products by vitamins.
STUDY OF VITAMIN COMPOSITION OF DIFFERENT SORTS OF BEETROOT
Republican scientific - practical center of hygiene, Minsk
*Institute of veqetabling NAS of Belarus, Minsk
The content of vitamins in different sorts of beetroot was studied. It is shown, that sorts
STUDY OF VITAMIN COMPOSITION OF MILK PRODUCTS BEING BROUGHT TO MARCETS OF MINSK
Republican scientific - practical center of hygiene, Minsk
The vitamin composition of milk and milk products being brought to markets of Minsk was studied. It is shown, that the whole milk products have determined vitamin composition.
THE CHARACTERISTIC OF RESIDUAL MICROFLORA OF FRUIT-AND-VEGETABLE CANNED FOOD
Belarusian state technological university, Minsk
The article is devoted to research of remaining microflora of modern canned products. The biochemical characteristics of microorganisms were described. Dominant species were identified as Bacillus subtilis-licheniformis group. The results of investigation on haemolytic activity and ability to produce lecithinase of non-pathogenic strains genus Bacillus are presented.
THE CHARACTERISTIC OF THE CARBOHYDRATES and FATTY COMPONENTS OF A FEED CHILDREN OF PRESCHOOL AGE OF REPUBLIC OF BELARUS
Belarusian medical academy postgraduate educations, Minsk
The hygienic estimation of a carbohydrate-fatty component of an actual feed for preschool children is carried out according to the recommendations accepted in Byelorussia and the WHO. Excess of receipt of the saturated fat acids and free sugar are established at insufficient receipt of complex carbohydrates that is a risk factor of development of excessive weight of a body in preschool children.
DETERMINATION OF HOLINE IN FORTIFIED BABY FOODS
Republican scientific - practical center of hygiene, Minsk
Unification spectrophotometrical method for the determination of holine fortified baby foods has been developed.
REDUCTION OF LOSSES OF VITAMINS AT MANUFACTURING VITAMINIZED MILK PRODUCTS
Republican scientific - practical center of hygiene, Minsk
The "know-how" of the dairy products enriched with vitamins should provide the maximal safety vitamins. To enrich with vitamins follows, first of all, the foodstuff providing their greatest safety. To reduce losses of vitamins by manufacture of the sour-milk products enriched with them selection special ferment cultures or application of the two-chamber packings providing mixing of vitamins with a sour-milk product directly ahead of the use allows.
AEROSOL METHOD OF DISINFECTION PROCESSING OF OBJECTS OF A TECHNOLOGICAL ENVIRONMENT OF THE FISH-CANNED ENTERPRISE
Republican scientific - practical center of hygiene, Minsk
The results of researches have shown, that use of a method of aerosol dispersion results in more significant reduction microbial contamination of a technological environment in comparison with a traditional method.
ESTIMATION OF RELATIVE BIOLOGICAL VALUE OF A PROTEIN COMPONENT OF CHILDREN'S CANNED FOOD BY IMPEDIMETRIC METHOD
Republican scientific - practical center of hygiene, Minsk
As a result of an estimation of biological value of skilled industrial samples of canned food for a children's feed is shown, that the introduction in the recipe of components, rich in protein, results in increase of relative biological value of products.
IMPEDIMETRIC METHOD OF DEFINITION OF RELATIVE BIOLOGICAL VALUE OF A PROTEIN COMPONENT OF FOODSTUFFS
Republican scientific - practical center of hygiene, Minsk
The method of definition of biological value of foodstuff on protozoa Tetrahymena pyriformis with use of principles of impedance technology is developed. Advantages of an impedance method of an estimation of biological value of foodstuff are profitability, high accuracy, sensitivity and reproducibility.
ROLE OF ALIMENTARY FACTORS IN MALIGNANT TUMOURS GENESE OF THE DIGESTIVE PATH AND VALUE OF AN EUTROPHY IN PREVENTIVE MAINTENANCE OF THE CANCER
Scientific research institute of oncology and medical radiology, Minsk
At present, basic oncology research on causes of cancer origination, its initial prevention and establishment of risk factors of cancer development is an issue of high priority in cancer control for many countries in the world. Our literature review deals with some alimentary factors having a role in the genesis of gastric, esophageal and intestinal cancer. Preventive elimination of baneful factors is a prophylactic measure against malignant neoplasms of the digestive tract.
APPLICATION OF ELECTROTHERMAL ATOMIC ABSORPTION SPECTROSCOPY FOR DETERMINATION OF SELENIUM IN BLOOD SERUM
Republican scientific - practical center of hygiene, Minsk
Efficiency of different ways of preparation of blood serum for determination of selenium by electrotermal atomic absorption spectroscopy is investigated. It is shown, that the best way is dilution of blood serum by application of nitric acid, Triton X-100, Antifoarm and palladium as modifier. Results of definition of selenium in blood serum by atomic absorption spectroscopy are in good conformity with the results received by fluometric method
CHARACTERISTIC OF MINERAL COMPOSITION OF VARIOUS KINDES OF BEET, CARROTS AND CABBAGE
Republican Scientific-Practical Center of Hygiene, Minsk
The contents of the basic macroelements (calcium, magnesium, phosphorus, sodium, potassium) in vegetable cultures is investigated: cabbage, carrots and beet of different kinds. It is shown, that the richest mineral structure characterizes beet of kinds < Egipetskaya ploskaya > and "Prigagunya", carrots of kinds "Lyavonicha", "Star" and "Leandr" and cabbage of kind "Mara".
INORGANIC SALTS INFLUENCE BY DETERMINATION OF SELENIUM IN FOODSTAFF BY ELECTROTERMIC ATOMIC ABSORPTION SPECTROSCOPY
Republican scientific - practical center of hygiene, Minsk
The influence of different contents of chlorides, sulfates and phosphates in solution on absorption signal of selenium is investigated. It was shown that use of nickel nitrate as modifier allows excluding the influences caused by presence of chlorides in solution. Presence of sulfates and phosphates in solution strongly reduces absorption signal of selenium. It is recommended to carry out the analysis of selenium in solutions with difficult matrix by method of standard additives.
BIOCHEMICAL CRITERIA OF AN PROTEINS ESTIMATION OF THE MEDICAL STUDENTS
Belarusian state medical university, Minsk
The paper presents the results of the assessment of proteins estimation of the medical students of the students of the Belarusian State Medical University. The informative indices are creatinine in urine, uric acid, total nitrogen, urea, amine nitrogen and quotient of protein food. They are widely adopted in hygienic and clinical investigations. It is determined that the protein of daily dietary intake is below the physiological line.
DETERMINATION OF THE OF ARSENIC IN COSMETICS BY THE METHOD OF ELECTROTERMAL ATOMIC ABSORPTION SPECTROMETRY
Republican scientific - practical center of hygiene, Minsk
It is proposed to carry out determination of arsenic in cosmetics by the method of ET AAS. ET AAS is more selective and sensitive that the photometry. It allows to decrease determination limit of method and to use modern methods of sample preparation.
THE CONTROL OF THE spoliage AND PATOGEN MICROFLORA FOR YOGHURT PRODUCTION
Republican scientific - practical center of hygiene, Minsk
Microbiological characteristics of yoghurt, their classification are being discussed in the article. Same attention is being paid to microbiological control of yoghurt production.
THE PROBLEM OF THE USE OF THE SPECIAL MICROFLORA FOR MANUFACTURED OF YOGHURT
Republican scientific - practical center of hygiene, Minsk
This article is devoted to the problem of the use of the special microflora of yoghurt. It has been proved that it is very important to determine quantitative and qualitative of microflora for to receive consuming properties of the product.
THE MAINTENANCE OF VITAMINS IN THE RATIONS OF THE NURSERY ORGANIZED COLLECTIVES
Republican scientific - practical center of hygiene, Minsk
In rations of children's homes and nursery preschool establishments of Minsk the maintenance of vitamins C, В1, В2, ?-carotin was investigated. Calculation of theoretical magnitudes of the maintenance of vitamins C, В1, В2, A in the rations was carried out. It was shown, that settlement and actual quantity of vitamin C (without taking into account a conducted С-vitaminization) and Thiamin in diets of children is much lower than norms of physiological requirements. The maintenance of Riboflavin and vitamin A, as a rule, provides physiological requirement.
FORTIFICATION FLOUR THE IMPORTANT STRATEGY IN THE FIGHT AGAINST MICRONUTRIENT DEFICIENCY
Belarusian medical academy postgraduate educations, Minsk
Mogilev state food university, Mogilev
The report is devoted to the actual problems of the fortification flour.
It was shown the possibility of the problem decision of micronutrient deficiency by manufacturing flour with improved vitamin and mineral composition.
IODINE INTAKE EVALUATION IN CHILDREN AND ADOLESCENTS LIVING IN IODINE DEFICIENT REGION
Belarusian medical academy postgraduate educations, Minsk
Minsk city endocrinology center, Minsk
International ecological university, Minsk
The aim of our study was to estimate iodine intake in children and adolescents living in Minsk region where active measures on elimination of iodine insufficiency have been carrying out from 1999, when the State program on Iodine Deficiency elimination was accepted.
DEFINITION DIQUAT, WORKING SUBSTANCE OF PREPARATION "REGLON", IN AN ONIONS AND A POTATO WITH A METHOD OF A HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY.
Republican scientific - practical center of hygiene, Minsk
It is offered high-selective and a sensitive method of definition of residual quantities diquat in a potato and an onions with application of high-performance liquid chromatography (HPLC). Conditions extraction, clearing of an extract and a method chromatographic the analysis are picked up. The limit of detection makes 0,01 mg / kg for a potato and 0,005 mg / kg for an onions.
RESEARCH AMINOACID OF STRUCTURE OF THE POTATO CONCENTRATE
Belarusian research & design institute for food products, Minsk
It is established, that the potato concentrate possesses the unique aminoacid's structure and can forms the base for the creation of the whole spectrum of drinks functional's assignment possessing the treatment-and-prophylactic action. The concentrate contain Gly, Ala, Val, Leu, Ile, Met, Phe, Tyr, Thr, Asp, Glu, Arg, His in amount 3,9; 8,1; 8,9; 5,4; 7,7; 1,5; 3,9; 2,6; 4,6; 37,8; 69,6; 15,8; 8,1 mg, accordingly in 100 g. The significant part of amino acids as a result of thermal processing a concentrate is spent for chemical reactions forming organoleptical properties.
CONDITION OF AN ACTUAL MEAL OF THE WORKERS ON THE ENTERPRISE "POLYMIR"
Republican scientific - practical center of hygiene, Minsk
Results of studying of an actual meal of workers of chemical enterprise "Polymir" at the Novopolotsk during the summer-autumnal and winter-spring periods are submitted.
Results of research have shown, that an actual meal of the workers is not adequate on power value, unbalanced on the basic nutrients. Insufficient power value of daily average diets of the surveyed groups workers, is caused mainly due to the insufficient contents of a carbohydrate component.
FOOD SUBSTANCES DANGEROUS ACTION THROUGH IMMUNE REACTIONS
Belarusian medical academy postgraduate educations, Minsk
Food and substances in them containing effects, on the one hand, accompanying by process of absorption and their introducing into body, on the other hand, food substances, as a environment components, will induce a series of reactions from the gut mucous, defining "one's own or foreigner". Food substances negative actions on a body are providing by substances antigenic properties and features of the body immune answer, thus can be formed three variants of reactions: full tolerance, local and-or system immune reaction with development immune intolerance. Examples of the negative immune inducible negative food substances are immunodeficiency conditions, hypersensitivity to gluten (celiac disease) and intestinal barrier permeability disturbances.
FOOD FLAVOURS AND METHODS OF THEIR DEFINITION
Republican scientific - practical center of hygiene, Minsk
Belarusian state university, Minsk
In given article classification, the basic methods of the analysis and sample preparation, parameters of an estimation of safety of flavoring substances are resulted. Safety of the industrial flavours, and also their amount in food stuffs is adjusted by the international organization of manufacturers food flavours and the national legislation. However, for the lack of methods of definition of food flavoring substances, there is a sharp necessity for their development in Republic of Belarus.
FEATURES OF MEAL AND CHARACTER DISPEPSIE IN THE REMOTE PERIOD AT PATIENTS TRANSFERRED CHOLECISTAECTOMIE
Grodno state medical university, Grodno
Aim. To evaluate long-term results in group of patients undergone laparoscopic cholecystectomy(LCE).
Material and methods. Special questionnaires from 187 patients 7-11 years after surgery were analyzed.
Results. Although 84,05% of the patients were satisfied with the results of surgery, 54,05% still complained of upper abdominal trouble. The best results were revealed in patients being on diet and taking medicines.
Conclusion. For practical reason a course of rehabilitation is recommended for all patients after LCE.
BIOMARKERS OF SELENIUM DEFICIENCY AND EFFICIENCY OF SELENIUM-CONTAINING SUBSTANCES
Institute of biochemistry, NAS of Belarus, Grodno
The activities of erythrocyte and blood plasma glutathione peroxidase isoenzymes as biomarkers of efficiency of Se-methionine, Se-pyrane or dimethyldipyrasolyl selenide (selecor) were studied when administered intragastrically to female albino Wistar rats at a dose of 250 ?gSe/kg body weight. H2O2-metabolizing activity did not change, but the Se-methionine treatment stimulated t-BOOH-metabolizing activity in erythrocytes. In blood plasma all the Se-containing compounds increased 1.3-2.2-fold glutathione peroxidase isoenzyme activity.
INTERACTIONS OF THE ESSENTIAL AND TOXIC MICROELEMENTS
Institute of biochemistry, NAS of Belarus, Grodno
*Grodno state medical university, Grodno
Brief review of the existent concepts about microelements interactions that include functional interconnection, competitive relations during absorption and bioavailability processes, negative consequences of the high dose intake and antagonistic actions of the toxic and essential elements. It is important to take into account contraindications for the microelements combinations and keep efficient batching regimen in the nutriceutical formula.
SELENIUM CONTENT IN BLOOD PLASMA OF YOUNG WOMEN AND PUERPERAE
Grodno state medical university, Grodno
*National Institute of Public Health, Helsinki
**Institute of biochemistry, NAS of Belarus, Grodno
The blood plasma of young women aged 17 to 34 years showed a low Se concentration independently of the seasonal factor. A more pronounced decrease in the microelement level was observed during the pathologic course of pregnancy (inborn defects of fetus) and the puerperal period. The level of seleniumemia in funic blood was found to be extremely low (< 30 ug/l). The data obtained reflect Se consumption deficiency in women of childbearing age, dwellers of the Grodno province.
ABOUT THE NECESSITY OF NEW METHODS DEVELOPMENT OF ANHYDROUS ETHANOL MAINTENANCE DETERMINATION IN HIS WATER SOLUTIONS, PRODUCTION OF ALCOHOLIC BEVERAGE AND VINE INDUSTRY, IN BEER, OTHER LIGHT ALCOHOLIC DRINKS, JUICES FROM FRUITS AND BERRIES WITH ADDITIVES OF ETHANOL, PRODUCTS FROM FRUITS AND VEGETABLES PROCESSING WITH ADDITIVES OF ETHANOL AND IN KVASS AND SOFT DRINKS AS WELL
Republican scientific - practical center of hygiene, Minsk
The comparative estimation of existing all-union state standart methods of determination of a volumetric or mass fraction of anhydrous ethanol in various objects of alcoholic and nonalcoholic food production is given in the article. It is shown that they are manysided and their practical realization is long and complicated as well. The conclusion about the necessity of modern, reliable and fast tool methods of development of ethanol analysis in the production of food industry is made.
METHODS FOR THE DETERMINATIONS OF B-GROUP VITAMINS (THIAMIN, RIBOFLAVIN, PYRIDOXINE AND FOLIC ACID) IN FOODS
Republican scientific - practical center of hygiene, Minsk
Methods for the determinations of b-group vitamins (thiamin, riboflavin, pyridoxine and folic acid) in food products were studied. it is shown, that high-performance liquid chromatographic method is more suitable for the analysis of b-group vitamins then others.
DETERMINATION OF SYNTHETIC COLOURS IN CONFECTIONERY
Republican scientific - practical center of hygiene, Minsk
The method for the determination of synthetic colours in confectionery was developed.
COMPARATIVE CHARACTERISTIC OF AMINO ACIDS COMPOSITION OF GOAT, HUMAN AND CAW MILK
Republican scientific - practical center of hygiene, Minsk
The comparative characteristic of amino acids composition of goat, human and caw milk was carried out. It is determined, that goat milk contents the same essential amino acids like human milk.
STUDY ON QUANTATITATIVE RADIOCHEMICAL STRONTIUM-90 DETERMINATION IN RAPE OIL BY DAUGHTER YTTRIUM-90 DETECTING
Republican scientific - practical center of hygiene, Minsk
An improved method is described for determination of the activity of strontium-90 in rape oil by daughter yttrium-90 detecting. The method is based upon extraction of daughter yttrium-90 with nitric acid-water compositions from rape oil samples treated with yttrium, cesium and strontium stable isotope carriers. Optimal daughter yttrium-90 extraction conditions are determinated to prepare the scoring patterns with maximal yttrium-90 content. The results of analyses of rape oil samples contaminated with a known activity of strontium-90 agreed well with the expected values.
NEW DATA ON LEVEL OF VITAMINS AND MINERAL SUBSTANCES IN BREAST MILK
Institute of nutrition, Russian Academy of medical sciencies, Moscow
*Republican scientific - practical center of hygiene, Minsk
The review deals with some new data on vitamins and mineral substances in breast milk
EVALUATION OF SOME SWEETENING AGENTS SAFETY.
Institute of nutrition, Russian Academy of medical sciencies, Moscow
Republican scientific - practical center of hygiene, Minsk
The review deals with data on some sweetening agents safety.
ABOUT WAYS OF PERFECTION OF METHODOLOGY OF REGULATION RADIONUCLIDS IN FOOD
Belarusian medical academy postgraduate educations, Minsk
The critical analysis of the technique for calculating permissible levels of Caesium-137 and Strontium-90 content in food-stuffs and drinking water according to the republican norms has been made in the article, ways for further optimization of this technique being included.
FATTY ACID COMPOSITION AND CONTENT OF ORGANOCHLORINE COMPOUNDS IN FISH AND biologically active additiONS CONSUMED BY THE POPULATION OF THE REPUBLIC OF BELARUS
Republican scientific - practical center of hygiene, Minsk
Fish from Belarus, fish oil and preparations with it, biologically active additions with vegetable oils were analyzed by gas chromatographic method. It was shown, that all the investigated samples contain high quantity of irreplaceable ?-3 and ?-6 polyunsaturated fatty acids. They are accessible sources of irreplaceable fatty acids. Also the contamination of fish and fish oil by organochlorine pesticide and polychlorinated biphenyls was analyzed. It was shown, that fish oil contains high percentage of these contaminants. Therefore, it can be stated that consumption of large amount of the fish oil as a source of polyunsaturated fatty acids can be dangerous for health.
FATTY ACIDS AND CHOLESTEROL CONTENT IN DIFFERENT SORTS OF ICE-CREAM
Republican scientific - practical center of hygiene, Minsk
Different sorts of ice-cream were analyzed by gas chromatographic method. Investigated samples contained milk powder, butter, cocoa, vegetable oils (coconut oil, palm oil, soy been oil). It was shown, that ice-cream with addition of coconut oil or palm oil contains small quantities of polyunsaturated fatty acids and cholesterol. Milk ice-cream with addition of liquid vegetable oils (soy been oil ) contains high percentage of polyunsaturated fatty acids. The content of cholesterol in such ice-cream is high. Investigation of fatty acids and cholesterol content will allow to give recommendation about rationalization of food.
EFFECTIVENESS OF THE MODULATORY INFLUENCE OF PHYTOCOMPOSITIONS "AURORA" ON THE FUNCTIONAL STATUS OF DEFEATED LIVER ACCORDING BIOCHEMICAL AND IMMUNO-HEMATOLOGIC INDICES
Republican scientific - practical center of hygiene, Minsk
*Belarusian state university, Minsk
**Belarusian state university informatics and radioelectronics, Minsk
Endogastric introduction of phytocompositions "Aurora" with doses 0.75 mg/kg to animals who received at the same time carbon tetrachloride was accompanied in the subchronical experiment by a significant tread effect in attitude toward investigated indices of cell and humoral parts of immunity and hematologic indices which values differed considerably from those of the animals with experimental hepatitis and were in the range of variations in the control group of animals. The complex biochemical estimation of marker indices of liver functions, content of peroxide oxidation products and a connected activity of antioxidant enzymes give an opportunity to suppose that the phytocompositions have the most pronounced hepato- membranetread impact during a defeat of the organ and are perspective.
THE USAGE OF FOOD ADDITIONS IN MANUFACTURE OF FUNCTIONAL IODINE ENRICHED FOODSTUFFS
Republican scientific - practical center of hygiene, Minsk
Many manufactures in the Republic of Belarus use iodine contained food additions for enriching different foodstuffs. Iodine content in the iodine contained food additions and foodstuffs (milk, eggs, chicken meat) enriched by these food additions, were investigated. It was shown, that the usage of the iodine contained food additions allows to enrich different foodstuffs effectively. The consumption of these enriched foodstuffs will allow to decrease the quantity of iodine deficient diseases in Belarus.
ATOPIC DERMATITIS AND FOOD ALLERGY
*Republican scientific - practical center of hygiene, Minsk
**Minsk municipal clinical dermatovenerologic dispensary, Minsk
***432-th Chief military clinical hospital, Minsk
Food allergy with dermatologic signs is more widespread among males (62,5 %). The leading etiologic agents are: citruses (56,3 %), eggs (40,6 %) and chocolate (28,1 %).
The levels of leucocytes, phagocyting activity of neutrofiles and T-cells of immune system are increased among the patients with dermatoses with a food allergy.
Pathology of gastrointestinal tract among the patients suffered from allergic dermatoses with a food hypersensitivity registered in 62,5 % of cases.
CLINICAL AND IMMUNOLOGICAL ASPECTS OF CROSS FOOD ALLERGY
*Republican scientific - practical center of hygiene, Minsk
**10-th municipal hospital, Minsk
***432-th Chief military clinical hospital, Minsk
The main clinical signs of food allergy among a patients with pollinoses are: syndrome of oral allergy (SOA) - 52,5 % of patients, urthicaria - 33, 3% of patients, dermatitis (28,6 %), oedema - 10,0 %. The immunologic disorders in the cases of food allergy are the next: increasing of B-lymphocytes' and immunoglolobuline M' levels. The main food allergens among the patients with the cross food and pollen allergy are: sunflowers, apples, carrot, citruses, nuts and honey.
HYGIENIC APPROACHES TO SETTING NORMS OF PHYSIOLOGICAL REQUIREMENTS OF CHILDREN OF PRESCHOOL AGE IN VITAMINS
Republican scientific - practical center of hygiene, Minsk
In article the hygienic approaches used by development of recommended sizes of consumption of vitamins are considered, and also the results of research reflecting the analysis of adequacy of receipt of vitamins with diets of children of preschool age, related to 1-2 groups of the health, attending children's preschool establishments of Minsk are submitted, to physiological requirements of an organism. Criteria for an estimation of adequacy of the maintenance of vitamins in diets of children of preschool age are determined. Results of the carried out researches are used by preparation of the instruction
SOME RESULTS OF STUDYING OF HERBS IN REPUBLIC BELARUS
Republican scientific - practical center of hygiene, Minsk
In article the data of biochemical research of elevated weight of plant Aruncus vylgare L are submitted.
On the basis of choramotgraphiс and spectrophotometric data and results of comparison with authentic substances have been identified: querzetin, caempferol, astragalin, isoquerzetin, rutin, and also chlorogenic, isochlorogenic, n-cumaric and coffee acids.
Analyzing biological features and a chemical compound Aruncus vylgare it is obvious, that it can serve as good addition of sources of raw material for development of medical products of Р-vitamin action.
ECOLOGICAL SAFETY OF FRUIT-AND-VEGETABLE TINNED PRODUCTS FOR A CHILDREN'S FEED
Belarusian state technological university, Minsk
Nitrate ion is ubiquitous in the environment arising from sources such as fertilisers and release from decaying vegetation. The significance of nitrate to human health derives primarily from the fact that nitrate can be converted in vivo to the nitrite ion, although there are some concerns about nitrate itself. The subject-matter of this work is the investigate concentration of nitrate/ nitrite ion in the storage of food for children from vegetation.
SAFETY OF VITAMINS IN FORTIFIED CONFECTIONERY
*Krasni pischevik, Bobruisk
Republican scientific - practical center of hygiene, Minsk
Percentage of safety of vitamins during production and storage of confectionery fortified by vitamin mixture was determined.
STUDY ON POTENTIAL GENOTOXICITY OF WATER TREATED WITH CHLORINE DIOXIDE
Republican scientific - practical center of hygiene, Minsk
The article deals with potential genotoxic properties of chlorine dioxide water solution (0,05 and 2,0 mg/l). Chlorine dioxide did not exhibit mutagenic activity in Ames'test with strains ТА 98 and TA 100 S. thyphimurium under conditions of metabolic activation and without it. However in the in vivo investigations, an increase in the number of cells with micronuclei and apoptosis signs in bone marrow cells of CBA mice was observed. In tests with snail Limnea stagnalis, the chlorine dioxide effect manifested itself first of all in animal death at its concentration in water of 2,0 mg/l. Besides, an increase in the number of apoptotic bodies and cells with death signs was noted in mantle liquid, with retardation of physiological reactions being observed at the same concentration. A rise in the number of clutches was observed as a response to the chlorine dioxide effect. Based on the investigations pursued, one may conclude about potential danger of chlorine dioxide for biota as a result of its ingress into pond and other reservoirs.
INFLUENCE OF INTERNAL 131I AND 137CS IRRADIATION ON PROCESSES LIPID PEROXYDATION IN RATS TISSUES
Grodno state university,
* Grodno state medical university, Grodno
The research into the effect of internal 131I and 137Cs irradiation on the function of rat liver showed that the "trace" of isotopes remained up to a year after the last administration. Within this period, wave-like process occurred related both to the increased and decreased efficiency of organelle functions, which indicated development of restoration adaptation processes in the animal organism.
INFLUENCE OF ENTEROSORBTION ON INFORMATION PARAMETERS THE SYSTEM OF LYSOSOMES OF A LIVER AT DIFFERENT STAGES OF FORMATION IN LIVER LESIONS IN EXPERIMENT
Republican scientific - practical center of hygiene, Minsk
*Belarusian medical academy postgraduate educations, Minsk
**Belarusian state medical university, Minsk
The analysis of information parameters intracellular structures allows to give an estimation of a structurally-functional condition system of lysosomes of a liver, their reserve opportunities and modifying influence of enterosorbtion.
TO THE QUESTION ON METHODOLOGY OF THE TOXICOLOGICAL ASSESSMENT AGROCHEMICALS AND MINERAL FERTILIZERS
Republican scientific - practical center of hygiene, Minsk
In the report the data on a substantiation of methodical approaches to a hygienic and toxicological evaluation of mineral fertilizers, agrochemicals, made with addition the waste products of and agrochemicals of complex composition are submitted. Demands for preparation of the sanitary - toxicological conclusion on each kind of fertilizings are determined.
EFFECTS OF HERBICIDE 2-METHYL-4-CHLORPHENOXYACETIC ACID ON OSSIFICATION OF BONES RUDIMENTS OF WHITE RATS EMBRYOS SKELETON
Republican scientific - practical center of hygiene, Minsk
*Belarusian state university informatics and radioelectronics, Minsk
It was shown, that the chemical 2М-4Х impacts on ossification of bones rudiments of white rats embryos skeleton in critical terms of pregnancy and at daily administration during all pregnancy.
ESTIMATION OF COMPLEX RISK OF INFLUENCE OF PESTICIDES ON WORKING
Republican scientific - practical center of hygiene, Minsk
Pesticides are one of the basic sources of environmental contamination. The significant share of used means of protection of plants falls at the preparations containing two and more working substance. With the purpose of prevention of their adverse influence, first of all, both on health working, and on an environment, it is necessary to carry out an estimation of risk at application of the combined pesticides in real conditions of application.
THE ORDER OF THE MANIPULATION WITH MEDICAL WASTE PRODUCTS
Republican scientific - practical center of hygiene, Minsk
The correct manipulation with medical waste products is a guarantee of safety for the serving medical personnel and the population. For the correct reference with medical waste products they have been divided into groups on a degree of their toxicological danger.
For republic creation and regulation of system of the manipulation with medical waste products is necessary.
MODERN HYGIENIC PROBLEM OF PHARMACEUTICALS WASTE DISPOSAL
Republican scientific - practical center of hygiene, Minsk
Pharmaceuticals waste represent serious real danger to the population and environment. In article methods of medicines waste neutralization and salvaging are discussed. Procedure of choice of disposal and processing of pharmaceuticals waste is high-temperature combustion.
EVAlUATION OF WASTE PHITOTOXICITY OF THE MINSK TRACTOR FACTORY
Republican scientific - practical center of hygiene, Minsk
Waste phytotoxicity of the Minsk tractor factory was studied on oats, cucumbers and a garden radish seeds and germs. It was obteined, that sludge of phosphatization baths and a dry paint waste decreased development of tests-cultures, that, probably, was connected to the increased contents of Zincum, Zinci sulfases and phosphates in the first waste and presence of phenolum at the second one.
MIGRATORY PARAMETERS EXOGENOUS CHEMICALS IN PEAT GROUND
Republican scientific - practical center of hygiene, Minsk
At research of migratory-aqueous and migratory-air parameters of substance having the various chemical nature, absence of migration was fixed from peat ground, both in long and in short-term experiments. Threshold limits of toxicants are determined on phytotranslocation parameter.
THE TOXICOLOGICAL AND HYGIENIC CHARACTERISTIC OF PHENANTHRENE
Republican scientific - practical center of hygiene, Minsk
In chronic experiment features of polyaromatic hydrocarbon phenanthrene biological effect were investigated, maximum noneffective dose determined as 0,1 mg/kg. The phenanthrene embryotoxic effect was demonstrated in a dose about 0,1 mg/kg. This dose is not toxic for adult organism. The threshold of specific embryotoxic effect was 0,01 mg/kg. Phenanthrene put to 2 classes of allergenic activity. Phenanthrene has no mutagen activity in Ames test.
SANITARY-HYGIENIC ESTIMATION OF THE DEPOSIT OF CLEARING CONSTRUCTIONS OF GALVANIC MANUFACTURE
Republican scientific - practical center of hygiene, Minsk
Studying of industrial wastes is an actual problem as they can represent danger to people and an environment. Studying of toxic properties of industrial wastes should be carried out in sharp and subacute toxicological experiments in view of results of chemical researches.
THE EFFECT OF PESTICIDE IZAPIN ON BIOCHEMICAL PARAMETERS IN RATS
Republican scientific - practical center of hygiene, Minsk
The ability of the pesticide and active substances to initiate toxic effects was estimated in subacute, subchronic and chronic experiments by daily intragastric administration to white not-thoroughbred rats.
The analysis of experimental results allows supposition that one of the substances - polyhexamethyleneguanidine hydrochloride (PHMG) exerts the most pronounced biological effect. Cell membranes are the most probable target for this substance. Thus, reduction in total lipids of blood serum against a background of an increase in total cholesterol was observed in the subacute experiment. These changes were accompanied by changes in water-mineral balance. A similar effect may be enhanced by a detergent under the action of a pesticide. It is difficult to reveal a target organ but judging by a drop in urea clearance and a dose-dependent rise in the content of albuminolysis end products in blood serum in a chronic experiment, PHMG exerts the most pronounced effect on kidneys. Under administration of the preparative form, a similar effect is levelled owning to a decrease in the PHMG dose.
CHANGES IN MORPHOLOGICAL PARAMETERS OF LIVER AND KIDNEYS OF WHITE RATS IN CHRONIC EXPERIMENTS UNDER EXPOSURE TO POLYHEXAMETHYLENEGUANIDINE HYDROCHLORIDE
Republican scientific - practical center of hygiene, Minsk
The substance PHGH under intragastric administration during 6 months in dozes of 1,5 mg/kg and 15 mg/kg resulted to blood circulation upset and dystrophic changes in liver and kidneys.
EFFECT OF POLYHEXAMETHYLENEGUANIDINE HYDROCHLORIDE ON SOME PARAMETERS OF SPERMATOGENESIS
Republican scientific - practical center of hygiene, Minsk
The substance PHGH under intragastric administration during 6 months in dozes of 0.15, 1.5 and 15 mg/kg cause to modification of state of germinative epithelium and testicles of white rats.
DEMONSTRATION OF BIOLOGICAL EFFECTS OF EPIBRASSINOLIDE IN CHRONIC EXPERIMENT
Republican scientific - practical center of hygiene, Minsk
The plant stimulator epibrassinolide is the natural phytohormone synthesized analogue. In prolonged (4 month) inhalation toxicity study epibrassinolide caused biologically significant effects on a state of some biochemical and morphological parameters in blood serum, kidneys and adrenal glands.
TOXICOLOGICAL AND HYGIENIC ESTIMATION OF OXIDATED GRAPHITE
Republican scientific - practical center of hygiene, Minsk
It has been determined, that graphite oxidation by an admixture of sulfuric acid and ammonium persulphate with the purpose to change its physical constitution does not cause modification of toxicity parameters in experiments on animals.
TOXICITY AND DANGER OF PAINT AND VARNISH MATERIALS IN CONDITIONS OF UNITARY INTRAGASTRIC INFLUENCE
Republican scientific - practical center of hygiene, Minsk
In article results of studying of parameters of sharp intragastric toxicity of various paint and varnish materials are submitted. By experiments on white rats it is established, that paint and varnish materials in conditions of unitary intragastric influence concern to 4 class of danger.
MORPHOFUNCTIONAL CHANGES IN THE SOME ENDOCRINE BODIES OF RATS AT ACTION OF ACETATE OF LEAD
Institute of physiology, NAS of Belarus, Minsk
New data on histochemical and morphofunctional changes in the endocrine organs in immature animals (rats) in postnatal ontogenesis under prolonged action of small dozes of lead acetate were obtained. Change in the level of energy metabolism enzymes of insulocytes and in the structure of pancreatic islets; in morphohistochemical parameters, which indicated a decrease in the synthesis of thyroid hormones; and morphofunctional changes in organelles of hormone-producing ovarian cells (mitochondria and endoplasmic reticulum) were observed.
NFLUENCE OF MANGANESE ON COGNITIVE FUNCTIONS OF EXPERIMENTAL ANIMALS
*Federal State Scientific Institution Institute of Toxicology Federal Medical- Biological Agency of Russian Federation, Saint-Petersburg
**Republican scientific - practical center of hygiene, Minsk
There was shown that process of training of animal suffers first of all as a result of sharp and chronic intoxication by manganese. This phenomenon can be caused by superfluous accumulation of manganese in subcortical nucleus of the brain.
PELARGONIC ACID MORPHOLIDE - INFLUENCE on the REPRODUCTIVE FUNCTION
*Federal state scientific institution institute of toxicology federal medical - biological agency of Russian Federation, Saint-Petersburg
**Republican scientific - practical center of hygiene, Minsk
Experiments of PAM influence study on reproductive function were performed on pregnant female rats. The animals received intragastrically the PAM containing mixture with the dose 1/20 LD50 every day during all pregnancy. Evaluation embryotoxic effect carried out according to death of fetuses, before-implantation and post-implantation, general embryonic mortality as well length and weight fetuses. The index of chemical factors influence was a coefficient of induced embryonic death. General embryonic mortality was increased in 2,3 times, including before-implantation one - 2,2 times and post-implantation one - 3,2 times. High percent age of induced death was revealed.
SKIN RESORPTIVE EFFECT STUDYING OF THE NITROGEN MINERAL FERTILIZER
Republican scientific - practical center of hygiene, Minsk
*Belarusian state university informatics and radioelectronics, Minsk
We studied resorptive effect of the fertilizer 27I received at processing of a rocket oxidant. In experiments on mature white rats it was shown, that 20-fold epicutaneous exposure to the nitrogen fertilizer in the native form lead to some changes in biochemical parameters of liver, serum and peripheral blood picture of the experimental animals. Thus, fertilizer 27I has resorptive effect.
FEATURES OF THE BIOLOGICAL EFFECT OF THE MINERAL FERTILIZERS RECEIVED AT SALVAGING OF ROCKET OXIDANTS
Republican scientific - practical center of hygiene, Minsk
By the example of nitrogen fertilizer 20F, received at processing a composition of rocket oxidants such as "melange" with known chemical mixture, necessity of careful studying of a similar sort of products biological effects was shown for maintenance of their safety at the National economy use.
OXICITY ESTIMATION IN VIVO OF PLANTS GROWTH REGULATORS OF EPIN AND EPIN PLUS
Republican scientific - practical center of hygiene, Minsk
Toxicological investigation of plan protection agents "Epin" and "Epin plus" was pursued on the basis epibrassinolide and homobrassinolide. By the results of acute experiments the agents "Epin" and "Epin plus" are low toxic for warm-blooded animals and belong to substances of the 4-th class of danger according to the all-Union State Standard 12.1.007-76. The agents have not shown an irritant effect by single application to rat skin at the 1600 mg/kg dose and 4-hour exposure. Irritation of mucous membranes was caused by ethyl alcohol and a surface-active substance (SAS) involved in the agent composition.
In the subchronic experiment, the agent "Epin" increased the amount erythrocytes, caused in rise in haemoglobin and a hematocrit in animals; reduced triacylglyceride content of blood serum and gave rise to an increase in excretion of albuminolysis and products with urine. Most changes in other physiological, biochemical, hematological indices were due to a toxic effect of the SAS and ethanol mixture.
Thus, the agents "Epin" and "Epin plus" exhibit moderately pronounced general resorptive effects which predominantly manifest themselves by changes in indices of erythropoesis, protein metabolism as well as of kidney function.
UNITIOL IN THE TREATMENT AND IN THE PREVENTIONS OF THE REMOTE CONSEQUENCES OF THE EYE DAMAGES RESULTING FROM GAS WEAPONS
*Federal State Scientific Institution Institute of Toxicology Federal Medical-Biological Agency of Russian Federation, Saint-Petersburg
**Republican scientific - practical center of hygiene, Minsk
In our real life there often occur eye damages resulting from chemical factor of gas weapons such as gas balloons and gas pistols from a short distance. In such cases chemical burns of the eyes may result in corneal opacity and impairment of vision. The purpose of our work is to study the effect of antidote - unitiol, on the development of eye diseases associated with chemical burns. Using deferent gas weapons we cause burn damages in the eyes of rabbits. Then we treat these burns with unitiol and observe and follow the process of recovery. The conclusion of this work is the use of antidote for the treatment ocular chemical burns and in the prevention of the remote consequences of the eye damages resulting from gas weapons is effective.
SUBSTANTIATION OF METHODOLOGY OF EXOGENOUS CHEMICALS REGULATION IN PEAT GROUND
Republican scientific - practical center of hygiene, Minsk
The Instruction 2.1.7.11-12-205-2003
COMPLEX TOXICOLOGO-HYGIENIC RESEARCHES MINERAL FEED ADDITIVES
Republican scientific - practical center of hygiene, Minsk
Belarusian state university informatics and radioelectronics, Minsk
In article results complex sanitary-chemical, radiological, microbialogic and toxicological researches of mineral feed additives by results of which they estimated as safe compositions are introduced.
TOXICOLOGICAL EVALUATION POLYMETALLIC THE MODIFICATOR OF CONCRETE
Republican scientific - practical center of hygiene, Minsk
In paper results of toxicological examinations of the polymetallic modificator of the concrete intended to use in the capacity of an antifreeze agent for an acceleration of induration of concrete are introduced. By results of studying the polymetallic modificator of concrete is recommended to application in production and a constructional engineering.
COMPLEX HYGIENIC EVALUATION OF BUILDING STUFFS ON THE BASIS OF WASTE PRODUCTS OF SLIMES BYELORUSSIAN METALLURGICAL MILL
Republican scientific - practical center of hygiene, Minsk
In paper results of sanitary-chemical, radiometric and toxicological examinations of an expanded clay, an expanded clay of the modified and filler of the modified, obtained of waste products Byelorussian metal works are introduced. By results of examinations stuffs are recommended to application in the civil and production building.
TOXICOLOGICAL-HYGIENIC ASSESSMENT OF MINERAL FERTILIZERS-"POCHVOGRUNT MINERALAIZED" AND "MINERAL - EXTRA"
Republican scientific - practical center of hygiene, Minsk
In paper results of radiometric and toxicological explorations pochvogrunt mineralaized and fertilizings fluid "Mineral - Extra" are introduced. By results of analysis mineral fertilizers are recommended to application in an agriculture.
ENDOTHELIAL FUNCTION AND THE BLOOD OXYGEN TRANSPORT AT SMOKING AND NON-SMOKING PATIENTS WITH ISCHEMIC HEART DISEASE
Grodno state medical university, Grodno
Smoking can influence on and the blood oxygen transport indices.
The aim of the study was to investigate the influence of smoking on endothelial function and indices in healthy subjects and patients with ischemic heart disease.
The present data indicate that smoking associated with impairment of endothelium-dependent vasodilatation and decreased nitrate/nitrite plasma level in healthy volunteers and patients with ischemic heart disease. Smoking leads to diminished pvO2, SvO2, p50 and a raised pCO2 and haemoglobin level in patients with ischemic heart disease.
Conclusion. Smoking disturbs endothelial function and oxygen tissue supply, which take place in pathogenesis of ischemic heart disease and its complications. We need to take it into account during treating smoking patients with ischemic heart disease.
SOME FEATURES OF BIOLOGICAL ACTION FILIPENDULA HEXAPETALA
Belarusian medical academy postgraduate educations, Minsk
Toxicological studying water preparations Filipendula hexapetala Gilib. is lead. In experiences low toxicity of vegetative raw material is established on laboratory animals (white mice and white rats). In experiences vegetative a preparation strengthened display of a tobacco intoxication.
THE EFFECT OF HYPOKINETIC STRESS ON LIPID PEROXIDATION ACTIVITY, FREE AMINO ACIDS CONCENTRATIONS OF BRAIN IN RATS WITH EXPERIMENTAL HYPOTHYROIDISM.
Belarus States Medical University, Minsk
The intensity of lipid peroxidation, activity of antioxidant enzymes, concentration of glutamic acid and histidine in brain tissues was reducing at experimental hypothyroidism. It was observed activation of lipid peroxidation, increase of glutamic acid, histidine, taurine concentration, inadequate changes of antioxidant enzymes activity in brain tissues of rats with experimental hypothyroidism at hypokinetic stress.
DEVELOPING OF BLOOD LEAD CONTROL KIT (BLCK)
Federal State Scientific Institution Institute of Toxicology Federal Medical-Biological Agency of Russian Federation, Saint-Petersburg
*Republican scientific - practical center of hygiene, Minsk
Samples BLCK with various concentration of lead with use of donor blood and blood of rats are received as a result of the carried out researches. Applications BLCK raises accuracy and correctness of laboratory analyses in clinical practice.
TOXICOLOGICAL ASSESSMENTOF AGENT "BELHYDROFOB"
Republican scientific - practical center of hygiene, Minsk
In article results of a pilot research of toxicological properties of agent "Belhydrofob" in experience on white rats are introduced. It is shown, that the agent concerns on parameters of acute toxicity to 4 class of danger, has weak stimulating activity on mucous, is capable to infiltration through uninjured integuments and has weak cumulative activity. References on safe effecting and application of agent "Belhydrofob" are given.
HYGIENIC ASSESSMENT OF PLASTIFIER FOR CONCRETE AND SOLUTIONS GP-1
Republican scientific - practical center of hygiene, Minsk
In article results of a complex hygienic assessment of plastifier GP-1 are stated. Plastifier GP-1 is intended for application as the plasticizing additive for concrete, ferro-concrete designs and building solutions. Results of sanitary - chemical researches testify that application of plastifier GP-1 by effecting products from concrete does not result in abjection from them some formaldehyde, dibutyl phthalate and dioctylphthalate on air medium at temperatures 20 and 400С. On parameters of acute intragastric toxicity plastifier GP-1 (LD50> 7500 mg/kg), in conformity about the GOST 12.1.007-76 fall into to 4 class of danger. In conditions of single-pass influence of plastifier GP-1, it is capable to render stimulating action on mucosas an eye of rabbits and falls into to 1 class. Plastifier GP-1 has no stimulating action on integuments in conditions of repeated exposure. In the general part of intoxication, at through a dermal route of infiltration of plastifier GP-1 to an organism, determining value the activation of processes of oxidation of proteins and lipids, and also a function state antioxidation systems.
BREAKING OF STRUCTURALLY FUNCTIONAL PROPERTIES OF SERUM PROTEINS OF THE RATS, CAUSED BY INFLUENCE OF LOW CONCENTRATIONS OF DIBUTYL PHTHALATE IN VITRO
Republican scientific - practical center of hygiene, Minsk
In the present work results of researches of influence of dibutyl phthalate in concentrations 0,23 - 3,6 mM on structurally functional properties and serum proteins are introduced. It is shown, that addition of dibutyl phthalate into concentrations of 3,6 mm results in quenching the general fluorescence of serum proteins on ~ 35 % and indole amino-propionic acid - on 34 %, hence, downstroke of a luminescence of serum proteins is caused by contact DBP to oddments of indole amino-propionic acid. Conformational changes of serum proteins have been investigated with the help of proteinaceous fluorescent probe ANS.
ESTIMATION OF POTENTIAL MUTAGEN ACTIVITY OF SUBSTANCES AND THEIR COMBINATIONS MAINLY MIGRATING FROM POLYMERIC BUILDING MATERIALS
Republican scientific - practical center of hygiene, Minsk
In the given work results of researches of potential mutagen activity of formaldehyde, styrene, dibutyl phthalate and their combinations on strains S. typhimurium are submitted: TA 98 and TA 100 in variants without metabolic activation and in conditions of incomplete metabolic activation. By results of an estimation in taste Ames of potential mutagen activity of the investigated substances and their combinations in the investigated concentration, it is not fixed. Obtained results allow to ascertain, that existing hygienic rules allow to protect softly by way of a possible induction of the remote effects at influence of the investigated substances in the investigated combinations.
ALVEOLAR MACROPHAGES AND TUMOR MASS IN THE LUNGS AT THE COMBINED EFFECT OF THE LEAD SALT, CADMIUM AND IRRADIATION TO THE ORGANISM.
Institute of the radiobiology, NAS of Belarus, Gomel
The reaction of the free cellular elements of the alveolar wash-out of the rats at the combined effect of the gamma radiation and the cadmium and lead salts is expressed by the intense decrease of the quantity of the pulmonary wash-out cellular population.
Tumor effects of the combined irradiation and metall impact are synergic, more expressed among the young animals. The proper carcinogenic activity of the cadmium chloride and lead nitrate is shown. The high modifying influence of the radiation factor to the hard metal carcinogenic effects with their combined impact, which increases with the decrease of the irradiation dose, is noted.
RESEARCH МUTAGENIC ACTIVITY OF REGULATORS OF GROWTH OF PLANTS IN TEST ON INDUCTION GENE MUTATIONS AT SALMONELLA TYPHIMURIUM
Republican scientific - practical center of hygiene, Minsk
The results of researches potential of mutagenic of activity in the Ames test on Salmonella typhimurium TA 100 and TA 98 in conditions incomplete metabolic of activation in all cultivations, used in experiment, testify to absence mutagenic of activity of the submitted preparations.
ROLE OF SEROTONIN RECEPTORS IN THE MECHANISM OF NOCICEPTIVE RESPONSES DURING VERTICAL ACCELERATION EXPOSURE AND ANTIORTHOSTATIC HYPOKINESIA
Institute of physiology, NAS of Belarus, Minsk
In experiments on adult male rats, with tail-flick response to termal stimulation, it was found that blockade of 5-HT3-receptors (metoclopramide, ondansetron) decreased the hyperalgesic effect of antiorthostatic hypokinesia and enhanced antinociception, induced by vertical accleleration, while blockade of 5-HT2-receptors by cyproheptadine diminished the antinociceptive effect of vertical acceleration exposure.
BIOCHEMICAL AND IMMUNO-HEMATOLOGIC INDICES OF WHITE RATS ORGANISMS ON THE MODEL OF EXPERIMENTAL HEPATITIS
Republican scientific - practical center of hygiene, Minsk
*Belarusian state university informatics and radioelectronics, Minsk
Forming of an experimental hepatitis model in laboratory animals during subacute tests with introduction of high doses of hepatotropic poison - carbon tetrachloride is accompanied by a transgression of main marker enzyme activity, deregulation of peroxide oxidation processes and an antioxidative liver protection leads to an oppression of cell- phagocytal and humoral parts of immunity, significant shifts of red and white hematosis rise indices. Ascertained shifts prove an adequacy of an originating model of liver defeat.
PROCTOLOGIC COMPOSITION
Republican scientific - practical center of hygiene, Minsk
In experimental conditions the toxicologo-hygienic characteristic of implants proctologic composition a domestic production is given.
TOXYCOHYGIENIC PROPERTIES OF THE IMPROVER OF BEDROCK TORFOLIGNINOVOGO
Republican scientific - practical center of hygiene, Minsk
In experimental conditions toxicity estimated, radiological researches of an improver of bedrocks torfoligninovogo are lead, references on its safe effecting are given.
TOXICOLOGO-HYGIENIC RESEARCHES SYNTHETIC VALVES OF HEART "PLANIKS-E"
Republican scientific - practical center of hygiene, Minsk
In article results of complex toxicologo-hygienic researches of synthetic valves of heart "Planiks-E" intended for replacement of changed natural valves of heart of the person are submitted. It is shown, that the specified valves of heart by sanitary-chemical, organoleptic, microbialogic and toxicological criteria answer hygienic requirements and are recommended for clinical tests.
DESCRIPTION OF CHEMICAL AND TOXIC PROPERTIES OF MIXED FODDER DUST
Republican scientific - practical center of hygiene, Minsk
The samples of mixed fodder dust are characterized by low content of silicon dioxide and mineral remainder, but they have significant specific gravity of a soluble faction by protein. Mixed fodder dust and the extracts from it do not have much toxic, but they have irritating skin and mucous tunic properties.
SPECIAL FEATURES OF THE BIOLOGICAL ACTION OF THE EXTRACT OF THE MIXED FODDER DUST IN SUBCHRONICAL INHALATION EXPERIMENT
Republican scientific-practical center of hygiene, Minsk
The mixed fodder dust during inhalation influence on the animals on the level of currently allowed concentration causes formation in organism of allergic process.
TOXIC AND HIGIENIC ASSESSMENT OF MICROBIAL CULTURE-PRODUCER OF AMINO ACID L-PHENYLALANIN
Republican scientific - practical center of hygiene, Minsk
Belarusian state university informatics and radioelectronics, Minsk
The microbial preparation does not have virulent, toxigennic, toxic and irritating skin properties, but it displays strong allergic activity in response to inhalation effect.
CHARACTER OF IMMUNOTOXIC ACTION ON ORGANISM OF BACTERIAL CULTURE-PRODUCER OF L-PHENYLALANIN
Republican scientific-practical center of hygiene, Minsk
Immunotoxic action of new microbial preparation of culture-producer of L-phenylalanin Brevebacterium lactofermentum is characterized by formation at animal of allergic effect, displays of strong allergic activities and low immune modulation ability in response to chronic inhalation influence in maximum concentration.
NON-IMMUNOGENIC INFLUENCE OF THE MIXED FODDER DUST AND ITS EXTRACT ON THE ORGANISM'S CELLS-TARGETS
Republican scientific - practical center of hygiene, Minsk
Acting on cells-targets of organism in vitro the mixed fodder dust and its extracts in big doses show hemolytic activity, toxic ability for cells and cell membranes.
TOXICOLOGO-HYGIENIC CHARACTERISTIC OIL-POD-PRODUCTION WASTE KAPROLACTAM
Republican scientific - practical center of hygiene, Minsk
Results of toxicologo-hygienic and sanitary-chemical researches oil-POD-a waste kaprolactam are given; by results of received researches recommendations on safe reception and use in a paint and varnish industry are given.
TOXICOLOGICAL CHARACTERISTIC OF CHLORINE DIOXIDE
Republican scientific - practical center of hygiene, Minsk
Chronic toxicity of chlorine dioxide that was proposed for potable water disinfection was estimated. Every day СlO2 solutions were injected with gastric tube to males of white non-thoroughbred rats at concentrations at 0.05; 0.25; 1.0 and 2.0 mg/l.
Prolonged intragastric ingress of chlorine dioxide resulted in a number of toxic effects. The maximum dose led to a drop in the body weight of experimental animals and a decrease in relative coefficient of adrenal and thyroid glands weight. Relative coefficient of the liver weight increased at concentrations of 0.25, 1.0 and 2.0 mg/l.
Enzymatic activity of gamma-glutamyl transpeptidase at the two highest doses statistically significantly increased. A maximum СlO2 concentration also led to an increase in the level of reduced glutathione with a simultaneous increase in glucose concentration in blood serum. A dose-dependent increase in the methemoglobin level was shown in blood hemolysate at СlO2 solution concentrations of 0.25, 1.0, 2.0 mg/l. The methemoglobin level was increased by 48 % under the action of the maximum dose. The level of a urea and chlorides in blood serum of experimental animals statistically significantly exceeded control parameters at water concentrations СlO2 0.25, 1.0, 2.0 mg/l.